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The immunomodulators 6-mercaptopurine (6-MP) and azathioprine (AZA) are used in patients with inflammatory bowel disease (IBD) in whom remission is difficult to maintain with the aminosalicylates alone.

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However, serologic markers do not appear to predict response to medical therapy, and there is currently insufficient evidence to recommend the use of antibody testing to predict responses to treatment or surgery in patients with IBD.

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Dose-ranging study of mesalamine (PENTASA) enemas in the treatment of acute ulcerative proctosigmoiditis: results of a multicentered placebo-controlled trial.

My doctor says Remicade is a last resort and wants to put me on Methotrexate, but I'm scared.

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This would not be the right forum to discuss the side effect profile of a drug, but methotrexate does not have the same association with pancreatitis as 6-MP.

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My 19 year old Daughter Kelly was diagnosed with UC about 3-4 years ago.

What sort of research did the Italian team do to find the causes of Crohn's?

After starting 6MP, you may notice some nausea or decreased appetite.

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